New-Onset Status Epilepticus in an 11-year-old Patient with Thyroid Autoimmune Dysfunction: A Case Report of Pediatric Hashimoto Encephalopathy

Aldo F. Costa; Joaquín A. Fernández-Ramos; Cristina Cazorla; Eduardo López-Laso

doi:10.1055/s-0044-1788053

Journal of Pediatric Epilepsy, Table of Contents

Journal of Pediatric Epilepsy 2024; 13(04): 092-095
DOI: 10.1055/s-0044-1788053

Case Report

New-Onset Status Epilepticus in an 11-year-old Patient with Thyroid Autoimmune Dysfunction: A Case Report of Pediatric Hashimoto Encephalopathy

Authors

Aldo F. Costa

¹Department of Neurology, Reina Sofía Hospital, Córdoba, Spain
Joaquín A. Fernández-Ramos

²Department of Paediatrics, Paediatric Neurology Unit, Reina Sofía Hospital, Córdoba, Spain

³Pediatric Metabolism Research Group, Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), Córdoba, Spain

⁴Clinical Research Group, Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), Valencia, Spain

⁵Department of Medical and Surgical Sciences, University of Córdoba, Córdoba, Spain
Cristina Cazorla

⁶Department of Neurophysiology, Reina Sofía Hospital, Córdoba, Spain
Eduardo López-Laso

²Department of Paediatrics, Paediatric Neurology Unit, Reina Sofía Hospital, Córdoba, Spain

³Pediatric Metabolism Research Group, Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), Córdoba, Spain

⁴Clinical Research Group, Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), Valencia, Spain

⁵Department of Medical and Surgical Sciences, University of Córdoba, Córdoba, Spain

Abstract

Hashimoto encephalopathy (HE) is a neuropsychiatric syndrome associated with positive thyroid antibodies (Ab). Its pathophysiology is still in debate and pediatric cases are considered rare. We present a case of an 11-year-old girl with new-onset refractory status epilepticus (NORSE) who presented a good initial response to corticosteroids but then required a second line of treatment with mycophenolate. In children presenting with NORSE of suspected autoimmune origin and no identification of autoimmune encephalitis traditional Ab, HE must be considered.

Keywords

Hashimoto encephalopathy - thyroid dysfunction - status epilepticus

Full Text

References

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